Workflow

Pipeline for implementing end-to-end analysis

gcap.workflow()

GCAP workflow for gene-level amplicon prediction

gcap.workflow.seqz()

GCAP sequenza workflow for gene-level amplicon prediction

gcap.workflow.facets()

GCAP FACETS workflow for gene-level amplicon prediction

gcap.ASCNworkflow()

GCAP workflow for gene-level amplicon prediction from ASCN input

deploy()

Deploy Command Line Interface to System Local Path

Class

Package builtin class

fCNA

R6 class representing focal copy number amplification list predicted from a cohort

Analysis Wrapper

Core build block for constructing pipeline

gcap.runASCAT()

Run ASCAT on tumor-normal pair WES data files

gcap.runBuildflow()

Build data for prediction from ASCAT result files

gcap.runPrediction()

Run gene-level circular prediction

gcap.runScoring()

Summarize prediction result into gene/sample-level

gcap.runASCNBuildflow()

Build data for prediction from absolute copy number data

Individual Analysis Modules

Individual data processing and analysis functions

gcap.extractFeatures()

Extract sample and region level features

gcap.collapse2Genes()

Generate unified gene-level feature data

get_auc()

Get AUC value

mergeDTs()

Merge a list of data.table

overlaps()

Get overlaps of two genomic regions

Datasets

Builtin datasets

ec

Example ecDNA training data

ascn

Example allele specific copy number (ASCN) data

oncogenes

Oncogene list